LATEST RESEARCH NEWS BY ONCOTARGET:
- New Insights into p53: A Powerful Gene’s Role in Cancer Therapy
A new study from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, published in Oncotarget, reveals that the gene p53, long known as the “guardian of the genome,” may be even more powerful than previously thought. By studying it in non-cancerous human cells, researchers discovered how p53 stops risky cell growth and uncovered two new potential targets for cancer therapy. - Targeting SETDB1: A New Strategy for Treating Osteosarcoma
Despite decades of research, treatment for osteosarcoma has remained largely unchanged, especially for patients whose cancer spreads or returns. However, a growing body of evidence, summarized in the review “SETDB1 amplification in osteosarcomas: Insights from its role in healthy tissues and other cancer types,” published in Oncotarget, highlights the gene regulator SETDB1 as a potential key player in cancer progression, immune system evasion, and resistance to therapy. - When the Cure Becomes the Cause: A Rare Case of Cancer from Donor Cells
A young woman beat leukemia; however, nine years later, she faced a different blood cancer. This rare twist, reported recently in Oncotarget, reveals an unexpected risk of bone marrow transplants and opens new questions about long-term outcomes and donor screening.
ABOUT DR. MIKHAIL (MISHA) BLAGOSKLONNY:
It is with great sadness and heavy heart that we announce the recent passing of Dr. Mikhail (Misha) V. Blagosklonny, our beloved Editor-in-Chief. Misha succumbed to metastatic lung cancer after a courageous battle.
Dr. Blagosklonny will be remembered as a brilliant and extraordinary scientist who dedicated his life to science. He was a visionary thinker, who made highly original contributions to cancer and aging research that were often ahead of their time.
Dr. Blagosklonny was born into a family of scientists. His mother, Professor of Medicine Yanina V. Blagosklonnaya, specialized in endocrinology and was a talented teacher, mentoring several generations of medical students. His father, Professor Vladimir M. Dilman, was a brilliant gerontologist, endocrinologist and oncologist, known for being a very charismatic person. He was the first person to encourage Misha to think about nature, aging, and philosophy.
Misha was a theorist by nature. While in school, he was deeply interested in physics and dreamed of becoming a theoretical physicist. Eventually, he chose biology, driven to study aging and age-related diseases, including cancer. He started as an experimentalist, but over the years, he became a theoretical biologist. In a way, his dream came true.
Read the full tribute to Dr. Blagosklonny | @Blagosklonny
ABOUT ONCOTARGET.ORG:
Oncotarget.org publishes weekly articles describing new and trending research papers published by Oncotarget—an open access biomedical journal dedicated to the publishing of the latest oncology-focused, peer-reviewed research papers. Visit Oncotarget.net to hear directly from the distinguished network of authors who continue to publish their research with Oncotarget. Readers may also find information about community news and events sponsored by Oncotarget at Oncotarget.net.
ABOUT ONCOTARGET:
On September 15, 2022, Oncotarget was accepted again for indexing by MEDLINE. Oncotarget is now indexed by Medline/PubMed and PMC/PubMed.
Oncotarget is published by Impact Journals, based out of Orchard Park, New York. Impact Journals has a proven track record for reaching the standards of the Wellcome Trust Publisher Requirements and is included in their Wellcome Trust List of Compliant Publishers. Read about our rigorous Scientific Integrity Process.
The Editorial Board of Oncotarget is honored to feature several Nobel Prize winners. The Editorial Board also features winners of prestigious recognitions such as the Lasker Award and the Breakthrough Prize.
Oncotarget utilizes an open-access model. This means that the peer-reviewed research articles published in Oncotarget are distributed online, free of cost or other access barriers. Oncotarget’s mission has always been to make exceptional discoveries rapidly and widely available, eliminate borders between specialties by linking different fields of biomedical science to foster the applications of basic and clinical science.
CONTACT INFORMATION:
For those interested in learning more about Oncotarget or in contacting the Journal, please visit the website.
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